Serine/Threonine-Protein Kinase MARK1

Preferred Label : Serine/Threonine-Protein Kinase MARK1;

NCIt synonyms : MAP/Microtubule Affinity-Regulating Kinase 1; PAR1 Homolog C; Par1c; EC 2.7.11.1; EC 2.7.11.26; Par-1c; MARK1; MRK;

NCIt definition : Serine/threonine-protein kinase MARK1 (795 aa, 89 kDa) is encoded by the human MARK1 gene. This protein plays a role in the phosphorylation of microtubule-associated proteins (MAPs), which results in microtubule disassembly.;

Details

Origin ID

C150283;

UMLS CUI

C1430753;

Automatic exact mappings (from CISMeF team)
- Intestinal cell kinase [OMIM gene]
- Map/microtubule affinity-regulating kinase 1 [OMIM gene]
- Mitogen-activated protein kinase kinase kinase 20 [OMIM gene]
- ciliogenesis associated kinase 1 [ORDO Gene]
- mitogen-activated protein kinase kinase kinase 20 [ORDO Gene]
OMIM relation
- Map/microtubule affinity-regulating kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MARK1 protein, human [MeSH concept]
- MARK1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MARK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- UBA Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Microtubule Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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