NCIt definition : Insulin-like growth factor II (180 aa, 20 kDa) is encoded by the human IGF2 gene.
This protein plays a role in cellular growth, development, and mitogenesis.;
NCIt note : Similar to insulin, the full length insulin-like growth factor II precursor protein
is cleaved at positions 24 or 25 and at positions 91 and 180 to release a 67 or 66
amino acid growth factor and an 89 amino acid E peptide. The E peptide can be further
processed to release prepeptin. (UniProt);