" /> Progesterone Receptor - CISMeF





Preferred Label : Progesterone Receptor;

NCIt synonyms : Progesterone Receptor B; Pr; Nuclear Receptor Subfamily 3 Group C Member 3; PgR; PRB; Progesterone Receptor Isoform B; NR3C3;

NCIt definition : Progesterone receptor (933 aa, 99 kDa) is encoded by the human PGR gene. This protein is involved in the regulation of transcription.;

Alternative definition : NCI-GLOSS: A protein found inside the cells of the female reproductive tissue, some other types of tissue, and some cancer cells. The hormone progesterone will bind to the receptors inside the cells and may cause the cells to grow.;

NCIt note : There are two progesterone receptors isoforms, A and B. The UniProt references have isoform B as the canonical form. Isoform B is associated with the activation of SRC/MAPK signaling, which isoform A is unable to do. (UniProt);

NCI Metathesaurus CUI : CL1798377;

Codes from synonyms : CDR0000423248; CDR0000423251;

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Keyword's position in hierarchy(ies) : arborescence

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30/04/2024


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