Preferred Label : Levonorgestrel-Releasing Intrauterine System;
NCIt definition : A long-acting, hormone-releasing, intrauterine device consisting of a small, T-shaped,
polyethylene frame and a reservoired synthetic progesterone with progestational and
potential antineoplastic activities. After insertion of this system into the uterus,
the device slowly and gradually releases the hormone. Levonorgestrel acts by binding
to the progesterone receptor in the nuclei of target cells, resulting in transcription
activation and an alteration in protein synthesis. Subsequently, luteinizing hormone
(LH) activity and ovulation are suppressed. Levonorgestrel may also exhibit antiproliferative
activity in endometrial tissue.;
Drug name : Mirena;
Origin ID : C52193;
UMLS CUI : C1708694;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_target
https://www.has-sante.fr/jcms/p_3320608/fr/unasert-levonorgestrel
2022
false
false
false
France
insurance, health, reimbursement
Levonorgestrel-Releasing Intrauterine System
administration, intravaginal
intrauterine devices, medicated
plastic iud with progestogen
menorrhagia
contraception
contraceptive agents, female
evaluation of the transparency committee
levonorgestrel
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