Preferred Label : Vilaprisan;
NCIt synonyms : (8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(4-methylsulfonylphenyl)-17-(1,1,2,2,2-pentafluoroethyl)-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one;
NCIt definition : An orally available progestin and selective progesterone receptor modulator (SPRM),
with potential anti-progesterone and antineoplastic activities. Upon oral administration,
vilaprisan competitively binds to the progesterone receptor (PR) in progesterone-responsive
tissue and inhibits PR-mediated gene expression. This interferes with progesterone
activity in the reproductive system and may inhibit PR-mediated proliferative effects
in cells overexpressing PRs. As a result, this agent may suppress ovulation and inhibit
proliferation of endometrial tissue or uterine fibroid formation.;
UNII : IN59K53GI9;
InChIKey : JUFWQQVHQFDUOD-ANRPBIDPSA-N;
CAS number : 1262108-14-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1262108-14-4
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G-SRS /a ;
Molecule name : BAY 1002670; BAY-1002670;
NCI Metathesaurus CUI : CL551037;
Origin ID : C148505;
UMLS CUI : C4508937;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_target
