Mifepristone - CISMeF

Preferred Label : Mifepristone;

NCIt synonyms : (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one; 11-((4-dimethylamino) phenyl)-17-Hydroxy-17-(1-propynyl) Estra-4,9- dien-3-one; 11 Beta-[4-(N,N-dimethylamino)phenyl]-17alpha-(propyl-1-ynyl)-delta-4,9-estradiene-17 beta-ol-3-one;

NCIt related terms : Mifeprex; RU 486;

NCIt definition : A derivative of the synthetic progestin norethindrone with antiprogesterone activity. Mifepristone competitively binds to the progesterone receptor, resulting in inhibition of the effects of endogenous or exogenous progesterone. This agent also exhibits antiglucocorticoid and weak antiandrogenic activities.;

Alternative definition : NCI-GLOSS: A drug used to end early pregnancies. It is also being studied in the treatment of some types of cancer and other conditions. Mifepristone blocks the action of progesterone, a hormone that helps some cancers grow. It is a type of antiprogesterone.;

UNII : 320T6RNW1F;

InChIKey : VKHAHZOOUSRJNA-GCNJZUOMSA-N;

CAS number : 84371-65-3;

Drug name : Mifeprex; Mifegyne; Korlym;

Molecule name : RU 486; RU-38486; RU-486;

Chemical formula : C29H35NO2;

NSC code : 652104;

ChEBI ID : CHEBI:50692;

Codes from synonyms : CDR0000535560; CDR0000045326; CDR0000535559; NSC0652104;

Details

Origin ID

C655;

UMLS CUI

C0026088;

See also inter- (CISMeF)
- Product containing mifepristone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mifepristone [ICD-11 Extension code]
- Mifepristone (substance) [SNOMED CT concept]
- Product containing mifepristone (medicinal product) [SNOMED CT concept]
- mifepristone [ATC Code]
- mifepristone [Substance BNPC]
- mifepristone [MeSH concept]
- mifepristone [MeSH Descriptor]
Validated automatic mappings to BTNT
- mifepristone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Progesterone Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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