Levonorgestrel

Preferred Label : Levonorgestrel;

NCIt synonyms : D-(-)-Norgestrel; 18-Methylnorethisterone; (17Alpha)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one; 13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one;

NCIt related terms : L-norgestrel; Plan B;

NCIt definition : The levorotatory form of norgestrel and synthetic progestogen with progestational and androgenic activity. Levonorgestrel binds to the progesterone receptor in the nucleus of target cells, thereby stimulating the resulting hormone-receptor complex, initiating transcription, and increasing the synthesis of certain proteins. This results in a suppression of luteinizing hormone (LH) activity and an inhibition of ovulation, as well as an alteration in the cervical mucus and endometrium.;

Alternative definition : NCI-GLOSS: A form of the hormone progesterone that is made in the laboratory and used to prevent pregnancy. It is being studied in the prevention of ovarian and endometrial cancer, and in the treatment of other conditions. Levonorgestrel is a type of oral contraceptive.;

UNII : 5W7SIA7YZW;

InChIKey : WWYNJERNGUHSAO-XUDSTZEESA-N;

CAS number : 797-63-7;

Drug name : Plan B; Norplant; Mirena;

Chemical formula : C21H28O2;

ChEBI ID : CHEBI:6443;

Codes from synonyms : 01044; CDR0000543113; CDR0000562697; CDR0000562696;

Details

Origin ID

C47585;

UMLS CUI

C0023566;

Automatic exact mappings (from CISMeF team)
- Product containing levonorgestrel (medicinal product) [SNOMED CT concept]
- norgestrel [MeSH Descriptor]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Levonorgestrel [ICD-11 Extension code]
- Levonorgestrel (substance) [SNOMED CT concept]
- Product containing levonorgestrel (medicinal product) [SNOMED CT concept]
- levonorgestrel [ATC Code]
- levonorgestrel [Substance BNPC]
- levonorgestrel [ATC Code]
- levonorgestrel [MeSH concept]
- levonorgestrel [MeSH Descriptor]
Validated automatic mappings to BTNT
- levonorgestrel [ATC Code]
- levonorgestrel [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Progesterone Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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