Ethinyl Estradiol/Levonorgestrel

Preferred Label : Ethinyl Estradiol/Levonorgestrel;

NCIt synonyms : Ethinyl Estradiol-Levonorgestrel;

NCIt definition : A combination of two steroid sex hormones, an estrogen and a progestin, used for contraceptive purposes. Estradiol, the endogenous counterpart of ethinyl estradiol (EE), is the principal, most potent estrogen hormone produced by the ovaries and is vital to the maintenance of fertility and secondary sexual characteristics in females. Levonorgestrel is a synthetic progestogen. This drug combination prevents or delays ovulation and causes a variety of hormonal changes. Ethinyl estradiol inhibits the release of follicle stimulating hormone (FSH), thus suppressing the development of ovarian follicle; levonorgestrel inhibits the release of luteinizing hormone (LH), thus preventing ovulation. This combination of agents alters the endometrium in such a way as to discourage implantation. (NCI04);

Drug name : Levlite; Portia; Seasonique; Trivora; Aviane; Lessina; Alesse; Nordette; Levora; Enpresse; Seasonale; Microgynon;

Details

Origin ID

C29034;

UMLS CUI

C0717761;

Automatic exact mappings (from CISMeF team)
- ethinyl estradiol, levonorgestrel drug combination [MeSH concept]
- ethinyl estradiol-norgestrel combination [MeSH Descriptor]
Currated CISMeF NLP mapping
- Product containing ethinylestradiol and levonorgestrel (medicinal product) [SNOMED CT concept]
- ethinyl estradiol, levonorgestrel drug combination [MeSH Supplementary Concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ethinylestradiol, ethinyloestradiol with levonorgestrel [ICD-11 Extension code]
- Levonorgestrel with ethinylestradiol [ICD-11 Extension code]
- Product containing ethinylestradiol and levonorgestrel (medicinal product) [SNOMED CT concept]
- ethinyl estradiol, levonorgestrel drug combination [MeSH concept]
- ethinyl estradiol, levonorgestrel drug combination [MeSH Supplementary Concept]
- levonorgestrel and ethinylestradiol [ATC Code]
- levonorgestrel and ethinylestradiol [ATC Code]
- medroxyprogesterone and ethinylestradiol [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Estrogen Receptor [NCIt concept]
- Progesterone Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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