nicotine - CISMeF

Preferred Label : nicotine;

MeSH definition : Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.;

CISMeF synonym : bitartrate, nicotine; tartrate, nicotine;

MeSH hyponym : nicotine bitartrate; Nicotine Tartrate;

MeSH CAS label : pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-;

MeSH Related Number : nicotine bitartrate; R7M676M8YV; 54-11-5;

Registry Number MeSH : 54-11-5;

Related CAS MeSH : R7M676M8YV (Nicotine bitartrate);

MeSH annotation : /biosyn permitted if by plant;

Wikipedia link : https://en.wikipedia.org/wiki/Nicotine;

Codes EINECS : 200-193-3;

Is substance : O;

medicament (CISMeF) : O;

UNII : 6M3C89ZY6R;

Details

Origin ID

D009538;

UMLS CUI

C0028040;

ATC code(s)
- nicotine [ATC Code]
ATC code(s)
- nicotine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Nicotine Gum [NCIt concept]
- Nicotine poisoning (disorder) [SNOMED CT concept]
- cholinergic receptor nicotinic alpha 1 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 10 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 2 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 3 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 4 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 5 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 6 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 7 subunit [HGNC gene]
- cholinergic receptor nicotinic alpha 9 subunit [HGNC gene]
- cholinergic receptor nicotinic beta 1 subunit [HGNC gene]
- cholinergic receptor nicotinic beta 2 subunit [HGNC gene]
- cholinergic receptor nicotinic beta 3 subunit [HGNC gene]
- cholinergic receptor nicotinic beta 4 subunit [HGNC gene]
- cholinergic receptor nicotinic delta subunit [HGNC gene]
- cholinergic receptor nicotinic epsilon subunit [HGNC gene]
- cholinergic receptor nicotinic gamma subunit [HGNC gene]
- smoking [MedlinePlus Topic]
CISMeF manual mappings
- nicotine [Substance BNPC]
Currated CISMeF NLP mapping
- Nicotine [DeCS]
- Nicotine [LOINC component]
- Nicotine [ICD-11 Extension code]
- Nicotine [SMS substance]
- Nicotine [NCIt concept]
- Nicotine (substance) [SNOMED CT concept]
- nicotine [SNOMED Notion]
- nicotine [COVID-19 Thesaurus concept]
Indexing information
- 5'-hydroxycotinine-N-oxide [MeSH Supplementary Concept]
- TA-NIC [MeSH Supplementary Concept]
- cytisine [MeSH Supplementary Concept]
MedlinePlus topic(s)
- smoking [MedlinePlus Topic]
Pharmacological action(s)
- Smoking Cessation Agents [MeSH Descriptor]
- ganglionic stimulants [MeSH Descriptor]
- nicotinic agonists [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
Record concept(s)
- nicotine [MeSH concept]
- nicotine bitartrate [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-benzyl-4-phenylnicotinamidinium [MeSH Supplementary Concept]
- 2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo(3,2-h)isoquinoline [MeSH Supplementary Concept]
- 2,4,5,6-tetradeuterocotinine [MeSH Supplementary Concept]
- 2-anilinonicotinyl-pyrazolo(1,5-a)pyrimidine [MeSH Supplementary Concept]
- 3',3'-dideuteronicotine [MeSH Supplementary Concept]
- 3,4-dihydrometanicotine [MeSH Supplementary Concept]
- 4'-methylnicotine [MeSH Supplementary Concept]
- 4-(dimethylphenylsilyl)nicotine [MeSH Supplementary Concept]
- 4-hydroxynicotine [MeSH Supplementary Concept]
- 5'-acetoxy-N'-nitrosonornicotine [MeSH Supplementary Concept]
- 5'-cyanonicotine [MeSH Supplementary Concept]
- 5-fluoronicotine [MeSH Supplementary Concept]
- 5-iodonicotine [MeSH Supplementary Concept]
- 5-isothiocyanonicotine [MeSH Supplementary Concept]
- 5-methoxynicotine [MeSH Supplementary Concept]
- 6-((1-methyl-2-(pyridin-3-yl)pyrrolidin-3-yl)methoxy)hexanoic acid [MeSH Supplementary Concept]
- 6-(2-phenylethyl)nicotine [MeSH Supplementary Concept]
- 6-hydroxynicotine [MeSH Supplementary Concept]
- 6-n-propylnicotine [MeSH Supplementary Concept]
- 7,8-difluoro-1,2,3,4,5,6- hexahydro-1,5-methano-3-benzazocine [MeSH Supplementary Concept]
- K(s-nic)5(Ga2(N,N'-bis-(2,3-dihydroxybenzoyl)-1,4-phenylenediamine)3) [MeSH Supplementary Concept]
- N'-carbomethoxynornicotine [MeSH Supplementary Concept]
- N'-formylnornicotine [MeSH Supplementary Concept]
- N'-methylnicotinium [MeSH Supplementary Concept]
- N'-propylnornicotine [MeSH Supplementary Concept]
- N-(n-dec-9-enyl)nicotinium [MeSH Supplementary Concept]
- N-(n-oct-3-enyl)nicotinium [MeSH Supplementary Concept]
- N-4-azido-2-nitrophenylnornicotine [MeSH Supplementary Concept]
- N-methyl-N'-oxonicotinium [MeSH Supplementary Concept]
- N-methyl-nicotine [MeSH Supplementary Concept]
- N-methylnicotinium [MeSH Supplementary Concept]
- N-methylnicoton [MeSH Supplementary Concept]
- N-methylnornicotinium [MeSH Supplementary Concept]
- N-n-decylnicotinium [MeSH Supplementary Concept]
- N-n-octylnicotinium [MeSH Supplementary Concept]
- N-octanoylnornicotine [MeSH Supplementary Concept]
- SIB1663 [MeSH Supplementary Concept]
- ZY-1 compound [MeSH Supplementary Concept]
- fulleronicotine [MeSH Supplementary Concept]
- homoazanicotine [MeSH Supplementary Concept]
- metanicotine [MeSH Supplementary Concept]
- nazartinib [MeSH Supplementary Concept]
- nicotine 1-N-oxide [MeSH Supplementary Concept]
- nicotine N-glucuronide [MeSH Supplementary Concept]
- nicotine hydrazide [MeSH Supplementary Concept]
- nicotine imine [MeSH Supplementary Concept]
- nicotine monomethiodide [MeSH Supplementary Concept]
- nicotinium molybdophosphate resin [MeSH Supplementary Concept]
- nornicotine [MeSH Supplementary Concept]
- pseudooxynicotine [MeSH Supplementary Concept]
See also
- Nicotiana [MeSH Descriptor]
See also (suggested by CISMeF)
- Nicotine Chewing Gum [MeSH Descriptor]
- receptors, nicotinic [MeSH Descriptor]
See also inter- (CISMeF)
- Nicotine Measurement [NCIt concept]
- Product containing nicotine (medicinal product) [SNOMED CT concept]
- blood nicotine levels [CISMeF Querying Strategy]
- nicotine poisoning [SNOMED Notion]
- urinary nicotine levels [CISMeF Querying Strategy]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Nicotine [DeCS]
- Nicotine [NCIt concept]
- Nicotine [LOINC component]
- Nicotine (substance) [SNOMED CT concept]
- Nicotine agent (substance) [Inactive SNOMED CT concept]
- Product containing nicotine (medicinal product) [SNOMED CT concept]
- nicotine [ATC Code]
- nicotine [Substance BNPC]
- nicotine [SNOMED Notion]
Validated automatic mappings to BTNT
- NICOTINE BITARTRATE DIHYDRATE [SMS substance]
- NICOTINE TARTRATE [SMS substance]
- Nicotine Bitartrate [NCIt concept]
- Nicotine bitartrate dihydrate (substance) [SNOMED CT concept]
- nicotine [ATC Code]

Keyword's position in hierarchy(ies) :

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