SMO wt Allele - CISMeF

Preferred Label : SMO wt Allele;

NCIt synonyms : Gx; Smoothened, Frizzled Family Receptor Gene; SMOH; Smoothened, Seven Transmembrane Spanning Receptor Gene; Smoothened, Drosophila, Homolog Gene; FZD11; Frizzled Family Member 11 Gene; Smoothened Homolog (Drosophila) Gene; Smoothened, Frizzled Class Receptor wt Allele; Smoothened (Drosophila) Homolog Gene; CRJS; PHLS;

NCIt definition : Human SMO wild-type allele is located in the vicinity of 7q32.1 and is approximately 25 kb in length. This allele, which encodes protein smoothened, is involved in G protein-coupled receptor signal transduction in the sonic hedgehog signaling pathway.;

GenBank Accession Number : NM_005631;

Details

Origin ID

C51473;

UMLS CUI

C1704664;

OMIM relation
- Smoothened, frizzled class receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Skin Basal Cell Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Sonic Hedgehog Pathway [NCIt concept]
gene_plays_role_in_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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