Nicotine - CISMeF

Preferred Label : Nicotine;

NCIt synonyms : (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine; 1-Methyl-2-(3-pyridyl)pyrrolidine; beta-Pyridyl-alpha-N-methylpyrrolidine; NIC;

NCIt related terms : (-)-Nicotine;

NCIt definition : A plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either ganglionic stimulation in low doses or ganglionic blockage in high doses. Nicotine acts as an agonist at the nicotinic cholinergic receptors in the autonomic ganglia, at neuromuscular junctions, and in the adrenal medulla and the brain. Nicotine's CNS-stimulating activities may be mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and ACTH. As a result, peripheral vasoconstriction, tachycardia, and elevated blood pressure may be observed with nicotine intake. This agent may also stimulate the chemoreceptor trigger zone, thereby inducing nausea and vomiting.;

Alternative definition : NCI-GLOSS: An addictive, poisonous chemical found in tobacco. It can also be made in the laboratory. When it enters the body, nicotine causes an increased heart rate and use of oxygen by the heart, and a sense of well-being and relaxation. It is also used as an insecticide.;

UNII : 6M3C89ZY6R;

InChIKey : SNICXCGAKADSCV-JTQLQIEISA-N;

CAS number : 54-11-5;

Chemical formula : C10H14N2;

NSC code : 5065;

ChEBI ID : CHEBI:17688;

Codes from synonyms : 00839; NSC0005065; CDR0000439405;

Details

Origin ID

C691;

UMLS CUI

C0028040;

False automatic mappings
- niacin [MeSH Descriptor]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Nicotine [DeCS]
- Nicotine [LOINC component]
- Nicotine (substance) [SNOMED CT concept]
- Nicotine agent (substance) [Inactive SNOMED CT concept]
- Product containing nicotine (medicinal product) [SNOMED CT concept]
- nicotine [ATC Code]
- nicotine [Substance BNPC]
- nicotine [MeSH Descriptor]
- nicotine [SNOMED Notion]
- nicotine [MeSH concept]
Validated automatic mappings to BTNT
- nicotine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Bupropion/Nicotine [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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