Claudin-6 - CISMeF

Preferred Label : Claudin-6;

NCIt synonyms : Skullin; CLDN6; CLDN-6; Claudin 6;

NCIt definition : Claudin-6 (220 aa, 23 kDa) is encoded by the human CLDN6 gene. This protein is involved in the formation of tight junctions.;

Details

Origin ID

C117145;

UMLS CUI

C1570897;

Automatic exact mappings (from CISMeF team)
- Claudin 6 [OMIM gene]
- Skin [LOINC System]
- Skin [LOINC component]
- skin [MeSH Descriptor]
OMIM relation
- Claudin 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CLDN6 protein, human [MeSH concept]
Validated automatic mappings to NTBT
- claudin 6 [MeSH concept]
- claudin 6 [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CLDN6 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
- Tight Junction [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Anti-CLDN6 Antibody-drug Conjugate DS-9606a [NCIt concept]
- Anti-CLDN6 CAR T-cells [NCIt concept]
- Anti-CLDN6 Monoclonal Antibody ASP1650 [NCIt concept]
- Anti-CLDN6/CD3 Bispecific Antibody SAIL66 [NCIt concept]
- Antibody-drug Conjugate SC-004 [NCIt concept]
- Autologous Anti-CLDN6 CAR-NK Cells [NCIt concept]
- mRNA-encoded Anti-CD3/Anti-CLDN6 Bispecific Antibody BNT142 [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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