Serine/Threonine-Protein Kinase Receptor R3

Preferred Label : Serine/Threonine-Protein Kinase Receptor R3;

NCIt synonyms : ACVRLK1; Activin-A Receptor Type-II-Like-1 Protein; ACVRL1; EC 2.7.1.37; Activin A Receptor, Type II-Like Kinase; TGF-B Superfamily Receptor Type I; Serine/Threonine-Protein Kinase Receptor R3 Precursor; EC 2.7.11.30; TSR-I; SKR3; ALK-1; Activin Receptor-Like Kinase 1; Activin A Receptor Type II-Like 1;

NCIt definition : Serine/threonine-protein kinase receptor R3 (503 aa, 56 kDa) is encoded by the human ACVRL1 gene. This protein plays a role in serine/threonine phosphorylation, signal transduction and blood and lymph vessel formation.;

Details

Origin ID

C26613;

UMLS CUI

C1504731;

OMIM relation
- Activin a receptor, type II-like 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ACVRL1 protein, human [MeSH concept]
- ACVRL1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ACVRL1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Serine/Threonine Kinase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Lung [NCIt concept]
- Placenta [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Anti-ALK-1 Monoclonal Antibody GT90001 [NCIt concept]
- Ascrinvacumab [NCIt concept]
- Dalantercept [NCIt concept]
- Panulisib [NCIt concept]

Keyword's position in hierarchy(ies) :

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