" /> Beta-2-Glycoprotein 1 - CISMeF





Preferred Label : Beta-2-Glycoprotein 1;

NCIt synonyms : Apolipoprotein H; B2GPI; Beta(2)GPI; Activated Protein C-Binding Protein; Apo-H; Anticardiolipin Cofactor; APC Inhibitor; Beta-2-Glycoprotein I; APOH;

NCIt related terms : BETA-2 GLYCOPROTEIN 1;

NCIt definition : Beta-2-glycoprotein 1 (345 aa, 38 kDa) is encoded by the human APOH gene. This protein is involved in binding to phospholipids, glycosaminoglycans and other negatively charged substances.;

Alternative definition : CDISC: An antigen of the cardiolipin-binding protein encoded by the APOH gene. It can be considered as an autoantigen and is commonly associated with the autoimmune diseases antiphospholipid syndrome and systemic rheumatic diseases like systemic lupus erythematosus.;

NCIt note : Beta-2-glycoprotein 1 may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome. (EntrezGene);

NCI Metathesaurus CUI : CL524123;

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29/07/2025


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