Bavituximab - CISMeF

Preferred Label : Bavituximab;

NCIt synonyms : Chimeric Anti-Phosphotidylserine Monoclonal Antibody;

NCIt definition : A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.;

UNII : Q16CT95N25;

CAS number : 648904-28-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 648904-28-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Tarvacin;

Molecule name : PGN401;

Codes from synonyms : 61;

Details

Origin ID

C49088;

UMLS CUI

C1707382;

Currated CISMeF NLP mapping
- bavituximab [MeSH concept]
- bavituximab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bavituximab [MeSH Supplementary Concept]
- bavituximab [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Beta-2-Glycoprotein 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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