CDGSH Iron-Sulfur Domain-Containing Protein 2

Preferred Label : CDGSH Iron-Sulfur Domain-Containing Protein 2;

NCIt synonyms : Zinc Finger Protein ZCD2; MitoNEET-Related 1 Protein; Miner1; NAF-1; CDGSH Iron-Sulfur Domain Protein 2; Nutrient Deprivation Autophagy Factor 1; Nutrient-Deprivation Autophagy Factor-1; Endoplasmic Reticulum Intermembrane Small Protein; CISD2;

NCIt definition : CDGSH iron-sulfur domain-containing protein 2 (135 aa, 15 kDa) is encoded by the human CISD2 gene. This protein plays a role in the regulation of autophagy.;

NCIt note : CDGSH iron-sulfur domain-containing protein 1 binds the anti-diabetes drug, pioglitazone. This interaction stabilizes the iron-sulfur (2Fe-2s) cluster. (UniProt);

Details

Origin ID

C116301;

UMLS CUI

C2001281;

Automatic exact mappings (from CISMeF team)
- CDGSH iron sulfur domain 2 [ORDO Gene]
- CDGSH iron sulfur domain 2 [HGNC gene]
- Cdgsh iron sulfur domain protein 2 [OMIM gene]
- Nuclear assembly factor 1 ribonucleoprotein [OMIM gene]
- TNFAIP3 interacting protein 1 [ORDO Gene]
- Tnfaip3-interacting protein 1 [OMIM gene]
OMIM relation
- Cdgsh iron sulfur domain protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CISD2 protein, human [MeSH Supplementary Concept]
- CISD2 protein, human [MeSH concept]
gene_encodes_gene_product
- CISD2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Ligand Binding [NCIt concept]
- Metal Ion Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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