NT-3 Growth Factor Receptor

Preferred Label : NT-3 Growth Factor Receptor;

NCIt synonyms : NTRK3; NT3 Growth Factor Receptor; TRKC Tyrosine Kinase; TRKC; GP145-TRKC; Tyrosine Kinase Receptor C; Trk-C; Neurotrophic Tyrosine Kinase Receptor Type 3; gp145(trkC); EC 2.7.10.1; Neurotrophic Tyrosine Kinase Receptor Type-3; Neurotrophin 3 Receptor;

NCIt definition : NT-3 growth factor receptor (839 aa, 94 kDa) is encoded by the human NTRK3 gene. This protein is involved in ligand binding, tyrosine phosphorylation and neurotrophin-3-mediated signaling.;

Details

Origin ID

C33984;

UMLS CUI

C3853696;

OMIM relation
- Neurotrophic tyrosine kinase, receptor, type 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- NTRK3 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neurotrophin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Fms/Trk Tyrosine Kinase Inhibitor PLX7486 Tosylate [NCIt concept]
- Larotrectinib Sulfate [NCIt concept]
- Paltimatrectinib [NCIt concept]
- Pan-TRK Inhibitor ONO-7579 [NCIt concept]
- Repotrectinib [NCIt concept]
- Selitrectinib [NCIt concept]
- Utatrectinib [NCIt concept]
- Zurletrectinib [NCIt concept]
- c-Met/FLT3/TRK/CDK8/19 Inhibitor TSN084 [NCIt concept]

Keyword's position in hierarchy(ies) :

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