Integrin Alpha-2

Preferred Label : Integrin Alpha-2;

NCIt synonyms : ITGA2; VLA-2 Subunit Alpha; Integrin Subunit Alpha 2; Platelet Antigen Br; Collagen Receptor; GPIa; Platelet Glycoprotein GPIa; Platelet Membrane Glycoprotein Ia; Very Late Activation Protein 2 Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; CD49b Antigen;

NCIt definition : Integrin alpha-2 (1181 aa, 129 kDa) is encoded by the human ITGA2 gene. This protein plays a role in the adhesion of platelets and other cells to collagen and other extracellular matrix proteins.;

NCI Metathesaurus CUI : CL342372;

Details

Origin ID

C174148;

UMLS CUI

C5400894;

Automatic exact mappings (from CISMeF team)
- Collagen, type I, alpha, receptor [OMIM gene]
- Integrin, alpha-2 [OMIM gene]
- Platelet antigen HPA-5b (substance) [SNOMED CT concept]
- integrin alpha2 [MeSH Descriptor]
- integrin alpha2 [MeSH concept]
- integrin subunit alpha 2 [HGNC gene]
- integrin subunit alpha 2 [ORDO Gene]
- receptors, collagen [MeSH Descriptor]
- receptors, collagen [MeSH concept]
OMIM relation
- Integrin, alpha-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGA2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arf6 Signaling Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- Syndecan-2-Mediated Signaling Pathway [NCIt concept]
- VEGFR3 Lymphatic Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Integrin alpha-2 Inhibitor E7820 [NCIt concept]

Keyword's position in hierarchy(ies) :

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