Integrin alpha-2 Inhibitor E7820

Preferred Label : Integrin alpha-2 Inhibitor E7820;

NCIt synonyms : E7820;

NCIt related terms : E-7820;

NCIt definition : A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.;

UNII : TVH5K7949N;

CAS number : 289483-69-8;

Details

Origin ID

C61501;

UMLS CUI

C4520212;

Automatic exact mappings (from CISMeF team)
- N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- E7820 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- E7820 [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Integrin Alpha-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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