Roundabout Homolog 2

Preferred Label : Roundabout Homolog 2;

NCIt synonyms : ROBO2;

NCIt definition : Roundabout homolog 2 (1378 aa, 151 kDa) is encoded by the human ROBO2 gene. This protein plays a role in cell migration, axon guidance and ligand binding.;

NCIt note : Slit homolog 2 protein is a ligand for roundabout homolog 2.;

NCI Metathesaurus CUI : CL508201;

Details

Origin ID

C126776;

UMLS CUI

C4283895;

OMIM relation
- Roundabout guidance receptor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- ROBO2 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Migration Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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