Nuclear Receptor Subfamily 5 Group A Member 2

Preferred Label : Nuclear Receptor Subfamily 5 Group A Member 2;

NCIt synonyms : Fetoprotein-Alpha 1 (AFP) Transcription Factor; Hepatocytic Transcription Factor; hB1F; Fetoprotein Transcription Factor; Human B1-Binding Factor; Liver Receptor Homolog-1; Nuclear Receptor NR5A2; Alpha-1-Fetoprotein Transcription Factor; Liver Receptor Homolog 1; LRH-1; B1-Binding Factor, Hepatocyte Transcription Factor which Activates Enhancer II of Hepatitis B Virus; B1-Binding Factor; CYP7A Promoter-Binding Factor; NR5A2;

NCIt definition : Nuclear receptor subfamily 5 group A member 2 (541 aa, 61 kDa) is encoded by the human NR5A2 gene. This protein is involved in both transcriptional regulation and hormone binding.;

NCIt note : Nuclear receptor subfamily 5 group A member 2 regulates cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in the liver. (UniProt);

Details

Origin ID

C112512;

UMLS CUI

C1429901;

Automatic exact mappings (from CISMeF team)
- NR5A2 protein, human [MeSH Supplementary Concept]
- Nuclear receptor subfamily 5, group a, member 2 [OMIM gene]
- fetoprotein transcription factor [MeSH Supplementary Concept]
- fetoprotein transcription factor [MeSH concept]
- nuclear receptor subfamily 5 group A member 2 [HGNC gene]
OMIM relation
- Nuclear receptor subfamily 5, group a, member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NR5A2 protein, human [MeSH Supplementary Concept]
- NR5A2 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NR5A2 Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Maturity Onset Diabetes of the Young Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Embryogenesis [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Organogenesis [NCIt concept]
- Pattern Formation [NCIt concept]
- Phospholipid Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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