Sarcospan - CISMeF

Preferred Label : Sarcospan;

NCIt synonyms : KRAG; KRAS Oncogene-Associated Protein; Kirsten-RAS Associated Protein; SPN1; Kras Oncogene-Associated; Kirsten-Ras-Associated Protein; K-Ras Oncogene-Associated Protein; Microspan; SPN2; SSPN;

NCIt definition : Sarcospan (1304 aa, 144 kD) is a cell adhesion process protein that is encoded by the human SSPN gene and has roles in muscle contraction and cell adhesion.;

NCIt note : Sarcospan is a component of the sarcolemma dystrophin-glycoprotein complex (DGC) that spans the muscle plasma membrane and links the F-actin cytoskeleton with the extracellular matrix. (UniProt);

Details

Origin ID

C29997;

UMLS CUI

C0669134;

False automatic mappings
- Microscopy [LOINC method]
- microscopy [MeSH Descriptor]
OMIM relation
- Sarcospan [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SSPN protein, human [MeSH Supplementary Concept]
- SSPN protein, human [MeSH concept]
Validated automatic mappings to BTNT
- SSPN protein, human [MeSH concept]
- SSPN protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SSPN Gene [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Matrix Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Muscle Contraction [NCIt concept]

Keyword's position in hierarchy(ies) :

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