C-Type Mannose Receptor 2

Preferred Label : C-Type Mannose Receptor 2;

NCIt synonyms : Urokinase-Type Plasminogen Activator Receptor-Associated Protein; uPARAP; UPAR-Associated Protein; Urokinase Receptor-Associated Protein; Endocytic Receptor 180; C-Type Lectin Domain Family 13 Member E; CD280 Antigen; Macrophage Mannose Receptor 2; Urokinase Plasminogen Activator Receptor-Associated Protein; Endo180;

NCIt definition : C-type mannose receptor 2 (1479 aa, 167 kDa) is encoded by the human MRC2 gene. This protein is involved in remodeling of the extracellular matrix and may play a role in the tumorigenesis and metastasis.;

Détails

Origin ID

C104647;

UMLS CUI

C3537377;

OMIM relation
- Mannose receptor, C-type, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- MRC2 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Focal Adhesion [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Lectin [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Phagocytosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Extracellular Matrix Degradation [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-uPARAP ADC ADCE-D01 [NCIt concept]

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