GDNF Family Receptor Alpha-4

Preferred Label : GDNF Family Receptor Alpha-4;

NCIt synonyms : GDNF Receptor Alpha-4; Persephin Receptor; GDNFR-Alpha-4; GFR Receptor Alpha 4; GDNF Family Receptor Alpha 4; GFRA4; GFR-Alpha-4;

NCIt definition : GDNF family receptor alpha-4 (299 aa, 32 kDa) is encoded by the human GFRA4 gene. This protein is involved in tyrosine-protein kinase receptor Ret activation.;

Details

Origin ID

C180807;

UMLS CUI

C1436427;

OMIM relation
- Gdnf family receptor alpha-4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- GFRA4 protein, human [MeSH Supplementary Concept]
- GFRA4 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GFRA4 Gene [NCIt concept]
- Growth Factor Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Thyroid Gland Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Autologous Anti-GFRa4 CAR-TCR-zeta-4-1BB-expressing T-cells [NCIt concept]

Keyword's position in hierarchy(ies) :

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