Solute Carrier Family 12 Member 1

Preferred Label : Solute Carrier Family 12 Member 1;

NCIt synonyms : Kidney-Specific Na-K-Cl Symporter; Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2; SLC12A1;

NCIt definition : Solute carrier family 12 member 1 (1099 aa, 121 kDa) is encoded by the human SLC12A1 gene. This protein is involved in cotransport of sodium-potassium-chloride in renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa.;

Details

Origin ID

C207889;

OMIM relation
- Solute carrier family 12 (sodium/potassium/chloride transporter), member 1 [OMIM gene]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC12A1 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Ascending Limb of Henle's Loop [NCIt concept]
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients