Electrogenic Aspartate/Glutamate Antiporter SLC25A13, Mitochondrial

Preferred Label : Electrogenic Aspartate/Glutamate Antiporter SLC25A13, Mitochondrial;

NCIt synonyms : Calcium-Binding Mitochondrial Carrier Protein Aralar2; Solute Carrier Family 25 Member 13; SLC25A13; ARALAR-Related Gene 2; Mitochondrial Aspartate Glutamate Carrier 2; ARALAR2; Citrin;

NCIt definition : Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (675 aa, 74 kDa) is encoded by the human SLC25A13 gene. This protein is involved in the mitochondrial efflux of aspartate and entry of glutamate plus a proton.;

NCIt note : Neutral and basic amino acid transport protein rBAT is found as a disulfide-linked heterodimer with B(0, )-type amino acid transporter 1. (UniProt);

Details

Origin ID

C190629;

UMLS CUI

C1447730;

OMIM relation
- Solute carrier family 25 (citrin), member 13 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC25A13 protein, human [MeSH Supplementary Concept]
- SLC25A13 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC25A13 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Inner Mitochondrial Membrane [NCIt concept]
gene_product_has_biochemical_function
- Amino Acid Transporter [NCIt concept]
- Calcium Binding Protein [NCIt concept]
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EF-Hand Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_malfunction_associated_with_disease
- Citrullinemia Type II [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Energy Metabolism Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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