Platelet Membrane Glycoprotein 1b Beta Chain

Preferred Label : Platelet Membrane Glycoprotein 1b Beta Chain;

NCIt synonyms : Antigen CD42b-Beta; CD42c Antigen; GP-Ib Beta; GPIb-Beta; GPIbB; Glycoprotein Ibbeta;

NCIt definition : Platelet glycoprotein Ib beta chain (206 aa, 22 kDa) is encoded by the human GP1BB gene. This protein is involved in the modulation of platelet aggregation.;

Details

Origin ID

C126551;

UMLS CUI

C3852783;

Automatic exact mappings (from CISMeF team)
- CD42c antigens [MeSH concept]
- glycoprotein Ib platelet subunit beta [ORDO Gene]
- platelet glycoprotein GPIb-IX complex [MeSH Descriptor]
- platelet membrane glycoprotein IIb [MeSH Descriptor]
OMIM relation
- Glycoprotein ib, platelet, beta polypeptide [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- GP1BB protein, human [MeSH concept]
gene_encodes_gene_product
- GP1BB Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
- Platelet [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
gene_product_is_physical_part_of
- CD42 Complex [NCIt concept]
- Glycoprotein Ib/IX Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Platelet Activation [NCIt concept]
- Positive Regulation of Platelet Aggregation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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