CD42 Complex - CISMeF

Preferred Label : CD42 Complex;

NCIt synonyms : Platelet Glycoprotein Ib/V/IX Complex; CD42 Antigen; GPIb-V-IX; Glycoprotein Ib/V/IX Complex; GPIb/V/IX; Platelet Glycoprotein Ib-V-IX; Glycoprotein Ib-V-IX; CD42; CD42a-d Complex;

NCIt definition : A heterotetrameric protein complex expressed on the surface of platelets that is involved in promoting platelet adhesion to von Willebrand factor during wound healing. This non-covalent complex is comprised of glycoprotein 5 (GPV; CD42d), glycoprotein 9 (GPIX; CD42a), and glycoprotein Ib (GPIb). GPIb is a heterodimer comprised of platelet glycoprotein Ib alpha chain (GPIba; CD42b) covalently bound to platelet glycoprotein Ib beta chain (GPIbb; CD42c).;

NCI Metathesaurus CUI : CL504711;

Details

Origin ID

C126122;

UMLS CUI

C4283872;

Automatic exact mappings (from CISMeF team)
- CD42 [LOINC component]
- glycoprotein Ib-IX-V complex [GO term]
See also inter- (CISMeF)
- CD42 cells [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_plays_role_in_biological_process
- Coagulation Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Wound Repair [NCIt concept]
has_gene_product_element
- Platelet Glycoprotein IX [NCIt concept]
- Platelet Glycoprotein V [NCIt concept]
- Platelet Membrane Glycoprotein 1b Alpha Chain [NCIt concept]
- Platelet Membrane Glycoprotein 1b Beta Chain [NCIt concept]
related_to_genetic_biomarker
- GP1BA Gene [NCIt concept]
- GP1BB Gene [NCIt concept]
- GP5 Gene [NCIt concept]
- GP9 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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