Ryanodine Receptor 2

Preferred Label : Ryanodine Receptor 2;

NCIt synonyms : Cardiac Muscle Ryanodine Receptor; RYR-2; Cardiac Muscle Ryanodine Receptor-Calcium Release Channel; Type 2 Ryanodine Receptor; Cardiac-Type Ryanodine Receptor; RYR2; hRYR-2;

NCIt definition : Ryanodine receptor 2 (4967 aa, 565 kDa) is encoded by the human RYR2 gene. This protein is involved in the regulation of calcium ion transport and the stimulation of cardiac muscle contraction.;

NCI Metathesaurus CUI : CL775788;

Détails

Origin ID

C204961;

OMIM relation
- Ryanodine receptor 2 [OMIM gene]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- RYR2 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Myocardium [NCIt concept]
gene_product_has_associated_anatomy
- Calcium Channel [NCIt concept]
- Cellular Membrane [NCIt concept]
- Ion Channel [NCIt concept]
- Sarcoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Cardiac Muscle Contraction Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Homeostasis [NCIt concept]
- Cardiac Muscle Contraction [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Myogenesis [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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