60 kDa SS-A/Ro Ribonucleoprotein

Preferred Label : 60 kDa SS-A/Ro Ribonucleoprotein;

NCIt synonyms : TROVE Domain Family Member 2; SSA2; TROVE2; Sjoegren Syndrome Antigen A2; SS-A; Ro60 Autoantigen; 60 kDa Ribonucleoprotein Ro; RoRNP; RO60; Gastric Cancer Multi-Drug Resistance Protein; Sjoegren Syndrome Type A Antigen; Ro/SSA 60kDa; 60 kDa Ro Protein; Ro 60 kDa Autoantigen;

NCIt definition : 60 kDa SS-A/Ro ribonucleoprotein (538 aa, 61 kDa) is encoded by the human RO60 gene. This protein is involved in binding to Alu retroelements and certain small RNAs.;

NCIt note : Antibodies against normal cellular 60 kDa SS-A/Ro ribonucleoprotein are found in sera from patients with systemic lupus erythematosus (SLE).;

Details

Origin ID

C181112;

UMLS CUI

C0672520;

Automatic exact mappings (from CISMeF team)
- Ro60, Y RNA binding protein [HGNC gene]
- Trove domain family, member 2 [OMIM gene]
- ss-a [medical devices type]
OMIM relation
- Trove domain family, member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RO60 protein, human [MeSH Supplementary Concept]
- RO60 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- RO60 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- RNA Recognition Motif [NCIt concept]
gene_product_is_element_in_pathway
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Interferon Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- RNA Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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