ERBB2 Gene Product

Preferred Label : ERBB2 Gene Product;

NCIt synonyms : ERBB2 Protein;

NCIt definition : A protein encoded by the ERBB2 gene.;

NCIt note : The ERBB2 gene encodes two forms of ERBB2 protein. One is a transmembrane protein that forms a heterodimer to act as the heregulin/neuregulin receptor. The other is a secreted form that consists only of the extracellular domain. It is capable of disrupting ERBB2 dimers thereby inhibiting growth.;

Details

Origin ID

C45842;

UMLS CUI

C1707864;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- ERBB2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- ErbB Receptor Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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