Mitochondrial Carrier Homolog 2

Preferred Label : Mitochondrial Carrier Homolog 2;

NCIt synonyms : Met-Induced Mitochondrial Protein; Solute Carrier Family 25 Member 50;

NCIt definition : Mitochondrial carrier homolog 2 (303 aa, 33 kDa) is encoded by the human MTCH2 gene. This protein is involved in the modulation of mitochondrial polarization.;

NCIt note : Mitochondrial carrier homolog 2 can bind to a truncated form of the BH3-interacting domain death agonist protein. This complex promotes apoptosis. (J. Biol. Chem. 2012; 287:15016-15023.);

Details

Origin ID

C102900;

UMLS CUI

C3538739;

OMIM relation
- Mitochondrial carrier homolog 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- MTCH2 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Inner Mitochondrial Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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