Gap Junction Alpha-1 Protein

Preferred Label : Gap Junction Alpha-1 Protein;

NCIt synonyms : Gap Junction 43 kDa Heart Protein; Cx43; Connexin 43; Heart Connexin; Connexin-43; GJA;

NCIt definition : Gap junction alpha-1 protein (382 aa, 43 kDa) is encoded by the human GJA1 gene. This protein is involved in the regulation of the assembly of gap junctions.;

Details

Origin ID

C115172;

UMLS CUI

C1568716;

Automatic exact mappings (from CISMeF team)
- Gap junction protein, alpha-1 [OMIM gene]
- connexin 43 [MeSH concept]
- connexin 43 [MeSH Descriptor]
- gap junction protein alpha 1 [ORDO Gene]
- gap junction protein alpha 1 [HGNC gene]
OMIM relation
- Gap junction protein, alpha-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GJA1 protein, human [MeSH Supplementary Concept]
- GJA1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GJA1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Gap Junction [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Intercellular Transport Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Organogenesis [NCIt concept]
- Restricted Diffusion [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Cx43 Agonistic Monoclonal Antibody ALMB-0168 [NCIt concept]

Keyword's position in hierarchy(ies) :

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