Interleukin-27 Receptor Subunit Alpha

Preferred Label : Interleukin-27 Receptor Subunit Alpha;

NCIt synonyms : CRL1 Protein; T-Cell Cytokine Receptor; TCCR; WSX1; IL-27R-Alpha; Class-I Cytokine Receptor; IL-27 Receptor Subunit Alpha; Cytokine Receptor WSX-1; IL-27RA; Type I T-Cell Cytokine Receptor; T-Cell Cytokine Receptor Type 1; Cytokine Receptor-Like 1; ZcytoR1; IL-27R Subunit Alpha;

NCIt definition : Interleukin-27 receptor subunit alpha (636 aa, 69 kDa) is encoded by the human IL27RA gene. This protein is involved in both interleukin-27 signaling and Th1-type immune responses.;

Details

Origin ID

C21435;

UMLS CUI

C1431316;

OMIM relation
- Interleukin 27 receptor, alpha [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- IL27RA protein, human [MeSH Supplementary Concept]
- IL27RA protein, human [MeSH concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- IL27RA Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- CD4-Positive T-Lymphocyte [NCIt concept]
- Lung [NCIt concept]
- Lymphocyte [NCIt concept]
- Natural Killer Cell [NCIt concept]
- Spleen [NCIt concept]
- Thymus Gland [NCIt concept]
- Type 1 Helper Cell [NCIt concept]
- Type 2 Helper Cell [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- IL27-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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