Hematopoietic Progenitor Cell Antigen CD34

Preferred Label : Hematopoietic Progenitor Cell Antigen CD34;

NCIt synonyms : gp105-120; HPCA1;

NCIt related terms : CD34 antigen; CD34;

NCIt definition : Hematopoietic progenitor cell antigen CD34 (385 aa, 41 kDa) is encoded by the human CD34 gene. This protein plays a role in cell-cell adhesion and may have a role in leukocyte migration.;

NCIt note : A protein found on the surface of some bone marrow and blood cells. Glycoproteins found on immature hematopoietic cells and endothelial cells. They are the only molecules to date whose expression within the blood system is restricted to a small number of progenitor cells in the bone marrow.;

Codes from synonyms : CDR0000045638;

Details

Origin ID

C17280;

UMLS CUI

C5441748;

OMIM relation
- Cd34 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD34 [LOINC component]
- CD34 Ag [LOINC component]
- Lymphocyte antigen CD34 (substance) [SNOMED CT concept]
- antigens, CD34 [MeSH concept]
- antigens, CD34 [MeSH Descriptor]
- lymphocyte antigen cd34 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- CD34 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endothelial Cell [NCIt concept]
- Hematopoietic Stem Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- IL17 Signaling Pathway [NCIt concept]
- Lymphocyte Adhesion Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cellular Migration Process [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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