Triggering Receptor Expressed On Myeloid Cells 2

Preferred Label : Triggering Receptor Expressed On Myeloid Cells 2;

NCIt synonyms : Triggering Receptor Expressed On Monocytes 2; TREM-2; TREM2;

NCIt definition : Triggering receptor expressed on myeloid cells 2 (230 aa, 25 kDa) is encoded by the human TREM2 gene. This protein plays a role in macrophage and dendritic cell immune responses.;

Details

Origin ID

C125470;

UMLS CUI

C1143976;

Automatic exact mappings (from CISMeF team)
- Triggering receptor expressed on myeloid cells 2 [OMIM gene]
- triggering receptor expressed on myeloid cells 2 [ORDO Gene]
- triggering receptor expressed on myeloid cells 2 [HGNC gene]
OMIM relation
- Triggering receptor expressed on myeloid cells 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TREM2 protein, human [MeSH Supplementary Concept]
- TREM2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TREM2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Dendritic Cell [NCIt concept]
- Macrophage [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
- Triggering Receptors Expressed on Myeloid Cells Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-TREM2 Monoclonal Antibody PY314 [NCIt concept]

Keyword's position in hierarchy(ies) :

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