" /> Transthyretin - CISMeF





Preferred Label : Transthyretin;

NCIt synonyms : TBPA; Prealbumin; TTR; ATTR; Thyroxine-Binding Prealbumin;

NCIt definition : Transthyretin (147 aa, 16 kDa) is encoded by the human TTR gene. This protein is involved in both the binding and transport of retinol and thyroxine.;

NCIt note : Transthyretin is a homotetramer with two thyroxine binding sites. Less than 1% of plasma transthyretin is involved in thyroxine transport, while 40% is in a tight protein-protein complex with the plasma retinol-binding protein (RBP). The formation of the complex with RBP stabilizes the binding of retinol to RBP and decreases the glomerular filtration and renal catabolism of the RBP molecule. (UniProt);

NCI Metathesaurus CUI : CL1374644;

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05/07/2025


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