P2X Purinoceptor 2

Preferred Label : P2X Purinoceptor 2;

NCIt synonyms : Purinergic Receptor; P2X2; ATP Receptor; Purinergic Receptor P2X 2; P2RX2;

NCIt definition : P2X purinoceptor 2 (471 aa, 52 kDa) is encoded by the human P2RX2 gene. This protein plays a role in the mediation of ATP-dependent neurotransmission.;

NCIt note : A homotrimeric complex of P2X purinoceptor 2 forms the ligand-gated ion channel, where the ligand is extracellular ATP.;

Details

Origin ID

C204160;

UMLS CUI

C2745815;

OMIM relation
- Purinergic receptor p2x, ligand-gated ion channel, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- P2RY2 protein, human [MeSH Supplementary Concept]
- P2RY2 protein, human [MeSH concept]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- P2RX2 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Calcium Channel [NCIt concept]
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Plasma Membrane [NCIt concept]
- Postsynaptic Membrane [NCIt concept]
- Synapse [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Taste Transduction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Homeostasis [NCIt concept]
- Gustation [NCIt concept]
- Hearing [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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