Nuclear Receptor Subfamily 2 Group E Member 1

Preferred Label : Nuclear Receptor Subfamily 2 Group E Member 1;

NCIt synonyms : hTll; Tll; Nuclear Receptor TLX; NR2E1; Protein Tailless Homolog;

NCIt definition : Nuclear receptor subfamily 2 group E member 1 (385 aa, 43 kDa) is encoded by the human NR2E1 gene. This protein plays a role in the regulation of both retinal development and neural stem cell differentiation.;

NCIt note : Nuclear receptor subfamily 2 group E member 1 binds as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in addition to the 5' flanking nucleotides that determine receptor specificity. (UniProt);

Details

Origin ID

C200336;

OMIM relation
- Nuclear receptor subfamily 2, group e, member 1 [OMIM gene]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NR2E1 Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Histogenic Process [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Nervous System Development [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Sight [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients