Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2

Preferred Label : Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2;

NCIt synonyms : SR Ca(2 )-ATPase 2; Calcium Pump 2; SERCA2; Cardiac Ca2 ATPase; Calcium-Transporting ATPase Sarcoplasmic Reticulum Type, Slow Twitch Skeletal Muscle Isoform; ATP2A2; Endoplasmic Reticulum Class 1/2 Ca(2 ) ATPase; EC 3.6.3.8, Formerly; EC 7.2.2.10;

NCIt definition : Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (1042 aa, 115 kDa) is encoded by the human ATP2A2 gene. This protein plays a role in both heart contraction and ATP hydrolysis.;

Details

Origin ID

C106418;

UMLS CUI

C1567357;

Automatic exact mappings (from CISMeF team)
- ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 [ORDO Gene]
- ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 [HGNC gene]
- Atpase, ca(2+)-transporting, slow-twitch [OMIM gene]
- sarcoplasmic reticulum Calcium-Transporting ATPases [MeSH Descriptor]
OMIM relation
- Atpase, ca(2+)-transporting, slow-twitch [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ATP2A2 protein, human [MeSH Supplementary Concept]
- ATP2A2 protein, human [MeSH concept]
gene_encodes_gene_product
- ATP2A2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Cardiac Muscle Contraction Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Cardiac Muscle Contraction [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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