Major Facilitator Superfamily Domain-Containing Protein 8

Preferred Label : Major Facilitator Superfamily Domain-Containing Protein 8;

NCIt synonyms : MFSD8; Ceroid-Lipofuscinosis Neuronal Protein 7; Major Facilitator Superfamily Domain Containing Protein 8;

NCIt definition : Major facilitator superfamily domain-containing protein 8 (518 aa, 58 kDa) is encoded by the human MFSD8 gene. This protein is involved in the modulation of lysosomal functions.;

NCIt note : Major facilitator superfamily domain-containing protein 8 (MFSD8) contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the MFS transport small solutes through chemiosmotic ion gradients but the substrate transported by the MFSD8 protein is unknown. (EntrezGene and UniProt);

Details

Origin ID

C157082;

UMLS CUI

C2001954;

Automatic exact mappings (from CISMeF team)
- Major facilitator superfamily domain-containing protein 8 [OMIM gene]
- major facilitator superfamily domain containing 8 [ORDO Gene]
OMIM relation
- Major facilitator superfamily domain-containing protein 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MFSD8 protein, human [MeSH concept]
- MFSD8 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- MFSD8 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Lysosome [NCIt concept]
gene_product_has_biochemical_function
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysosome Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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