Roundabout Homolog 1

Preferred Label : Roundabout Homolog 1;

NCIt synonyms : H-Robo-1; Deleted in U Twenty Twenty; ROBO1;

NCIt definition : Roundabout homolog 1 (1651 aa, 181 kDa) is encoded by the human ROBO1 gene. This protein is involved in neuronal development.;

NCIt note : SLIT1 and SLIT2 are ligands for roundabout homolog 1.;

Details

Origin ID

C126590;

UMLS CUI

C0755410;

Automatic exact mappings (from CISMeF team)
- Roundabout guidance receptor 1 [OMIM gene]
OMIM relation
- Roundabout guidance receptor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ROBO1 protein, human [MeSH concept]
- ROBO1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- ROBO1 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Migration Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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