Interferon-Inducible Double-Stranded RNA-Dependent Protein Kinase Activator A

Preferred Label : Interferon-Inducible Double-Stranded RNA-Dependent Protein Kinase Activator A;

NCIt synonyms : Protein Activator of Interferon Induced Protein Kinase EIF2AK2; PKR-Associated Protein X; PRKRA; Protein Activator of the Interferon-Induced Protein Kinase; PKR-Associating Protein X; Protein Kinase, Interferon-Inducible Double-Stranded RNA-Dependent Activator;

NCIt definition : Interferon-inducible double-stranded RNA-dependent protein kinase activator A (313 aa, 34 kDa) is encoded by the human PRKRA gene. This protein is involved in RNA-induced silencing of transcription and the regulation of antiviral responses that are mediated by interferon and double-stranded RNA.;

NCIt note : Interferon-inducible double-stranded RNA-dependent protein kinase activator A may mediate the association of double-stranded RNA with interferon-inducible eIF2alpha kinase (EIF2AK2).;

Details

Origin ID

C204895;

OMIM relation
- Protein kinase, interferon-inducible double-stranded rna-dependent activator [OMIM gene]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- PRKRA Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Double-Stranded RNA Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ceramide Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Induction [NCIt concept]
- Ligand Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Interference [NCIt concept]

Keyword's position in hierarchy(ies) :

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