Heterogeneous Nuclear Ribonucleoprotein M

Preferred Label : Heterogeneous Nuclear Ribonucleoprotein M;

NCIt synonyms : M4 Protein; hnRNA-Binding Protein M4; CEA Receptor; N-Acetylglucosamine Receptor 1; hnRNP M;

NCIt definition : Heterogeneous nuclear ribonucleoprotein M (730 aa, 78 kDa) is encoded by the human HNRNPM gene. This protein plays a role in the mediation of RNA splicing.;

NCIt note : Heterogeneous nuclear ribonucleoprotein M also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. (EntrezGene); Heterogeneous nuclear ribonucleoprotein M acts as a receptor for carcinoembryonic antigen in Kupffer cells, and may initiate signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. (UniProt);

Details

Origin ID

C98157;

UMLS CUI

C1099360;

Automatic exact mappings (from CISMeF team)
- Heterogeneous nuclear ribonucleoprotein M [OMIM gene]
- Heterogeneous-Nuclear ribonucleoprotein group M [MeSH Descriptor]
- heterogeneous nuclear ribonucleoprotein M [HGNC gene]
OMIM relation
- Heterogeneous nuclear ribonucleoprotein M [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HNRNPM protein, human [MeSH Supplementary Concept]
- HNRNPM protein, human [MeSH concept]
- Heterogeneous-Nuclear ribonucleoprotein group M [MeSH concept]
- Heterogeneous-Nuclear ribonucleoprotein group M [MeSH Descriptor]
gene_encodes_gene_product
- HNRNPM Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nuclear Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- RNA Recognition Motif [NCIt concept]
gene_product_is_element_in_pathway
- Spliceosome Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Alternate Splicing [NCIt concept]
- Ligand Binding [NCIt concept]
- RNA Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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