Alternate Splicing

Preferred Label : Alternate Splicing;

NCIt synonyms : Alternative Splicing;

NCIt definition : Alternate Splicing is a process in which multiple protein isoforms or products are generated from a single gene as a result of splicing together different nonconsecutive exons during the processing of initially identical nascent transcripts of a gene into mature mRNA transcripts. An exon may be connected to any one of several alternative exons to form the mRNA and generate related proteins, often in a tissue or developmental stage specific manner.;

Details

Origin ID

C16280;

UMLS CUI

C0002345;

Automatic exact mappings (from CISMeF team)
- Alternative splicing [OMIConto index]
Currated CISMeF NLP mapping
- Alternative splicing [OMIConto structure]
- alternative splicing [MeSH Descriptor]
- alternative splicing [MeSH concept]
See also inter- (CISMeF)
- Alternative splicing [OMIConto index]
- Alternative splicing detection (Gene expression array analysis) [OMIConto index]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- Alternative splicing [OMIConto structure]
- alternative splicing [MeSH concept]
- alternative splicing [MeSH Descriptor]
biological_process_has_associated_location
- Gene Feature [NCIt concept]
biological_process_involves_gene_product
- Apoptotic BCL2L1-Antisense Long Non-Coding RNA [NCIt concept]
- Heterogeneous Nuclear Ribonucleoprotein H [NCIt concept]
- Heterogeneous Nuclear Ribonucleoprotein M [NCIt concept]
- KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 1 [NCIt concept]
- KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3 [NCIt concept]
- Ribonucleoprotein PTB-Binding 1 [NCIt concept]
- Zinc Finger Ran-Binding Domain-Containing Protein 2 [NCIt concept]
process_involves_gene
- ABALON Gene [NCIt concept]
- ABALON wt Allele [NCIt concept]
- HNRNPH1 Gene [NCIt concept]
- HNRNPH1 wt Allele [NCIt concept]
- HNRNPM Gene [NCIt concept]
- HNRNPM wt Allele [NCIt concept]
- KHDRBS1 Gene [NCIt concept]
- KHDRBS1 wt Allele [NCIt concept]
- KHDRBS3 Gene [NCIt concept]
- KHDRBS3 wt Allele [NCIt concept]
- RAVER1 Gene [NCIt concept]
- RAVER1 wt Allele [NCIt concept]
- ZRANB2 Gene [NCIt concept]
- ZRANB2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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