Tyrosine-Protein Kinase Receptor Tie-1

Preferred Label : Tyrosine-Protein Kinase Receptor Tie-1;

NCIt synonyms : Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains 1; Tyrosine-Protein Kinase Receptor TIE1; JTK14; TIE1; EC 2.7.10.1; Protein Receptor Tyrosine Kinase TIE 1; Protein Receptor Tyrosine Kinase-TIE1; Tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1;

NCIt definition : Tyrosine-protein kinase receptor Tie-1 (1138 aa, 125 kDa) is encoded by the human TIE1 gene. This protein plays a role in tyrosine phosphorylation and angiogenesis.;

Details

Origin ID

C30100;

UMLS CUI

C1335549;

OMIM relation
- Tyrosine kinase with immunoglobulin and egf factor homology domains 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]
- TIE1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- EGF-Like Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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