Transmembrane Protein 41B

Preferred Label : Transmembrane Protein 41B;

NCIt synonyms : Protein Stasimon; Stasimon; TMEM41B;

NCIt definition : Transmembrane protein 41B (291 aa, 33 kDa) is encoded by the human TMEM41B gene. This protein plays a role in autophagy and certain types of viral infection.;

NCIt note : Transmembrane protein 41B is a host factor required for infection by human coronaviruses, including SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E, and flaviviruses, including Zika virus and Yellow fever virus. (UniProt);

NCI Metathesaurus CUI : CL1374984;

Details

Origin ID

C179737;

UMLS CUI

C5197217;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TMEM41B protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- TMEM41B Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cytoplasm [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Intracellular Transport [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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