T-Cell Surface Protein Tactile

Preferred Label : T-Cell Surface Protein Tactile;

NCIt synonyms : CD96 Antigen; CD96; Cell Surface Antigen CD96; T Cell-Activated Increased Late Expression Protein;

NCIt definition : T-cell surface protein tactile (585 aa, 66 kDa) is encoded by the human CD96 gene. This protein may play a role in immunoregulation.;

NCIt note : T-cell surface protein tactile binds the poliovirus receptor (PVR) and may function as a checkpoint inhibitor. (https://www.sciencedaily.com/releases/2018/12/181206120012.htm);

NCI Metathesaurus CUI : CL937001;

Details

Origin ID

C157303;

UMLS CUI

C4761611;

Automatic exact mappings (from CISMeF team)
- CD96 antigen [MeSH Supplementary Concept]
- CD96 antigen [MeSH concept]
- CD96 molecule [ORDO Gene]
- CD96 molecule [HGNC gene]
- Cd96 antigen [OMIM gene]
OMIM relation
- Cd96 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD96 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- T-Lymphocyte [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Matrix Adhesion Process [NCIt concept]
- Immunologic Factor Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Nelistotug [NCIt concept]

Keyword's position in hierarchy(ies) :

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