Macrophage-Stimulating Protein Receptor

Preferred Label : Macrophage-Stimulating Protein Receptor;

NCIt synonyms : c-Met-related Tyrosine Kinase; MST1R; MSP Receptor; Macrophage Stimulating Protein Receptor; EC 2.7.10.1; Macrophage Stimulating 1 Receptor; Antigen CD136; Protein-Tyrosine Kinase 8; p185-Ron; CDw136; CD136; Macrophage Stimulating-1 Receptor;

NCIt definition : Macrophage-stimulating protein receptor (1400 aa, 152 kDa) is encoded by the human MST1R gene. This protein is involved in ligand binding, tyrosine phosphorylation and signal transduction.;

NCIt note : Macrophage-stimulating protein receptor is synthesized as a single polypeptide which is processed to the 185-kD heterodimer of 35-kD (alpha) and 150-kD (beta) subunits joined by a disulfide linkage.;

Details

Origin ID

C28526;

UMLS CUI

C0215510;

OMIM relation
- Macrophage stimulating 1 receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- MST1R protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- MST1R Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Macrophage Stimulating 1 Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Glesatinib [NCIt concept]
- Narnatumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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