Neurexin-3-Beta

Preferred Label : Neurexin-3-Beta;

NCIt synonyms : Neurexin III-Beta;

NCIt definition : Neurexin-3-beta (637 aa, 69 kDa) is encoded by the human NRXN3 gene. This protein plays a role in cell adhesion.;

NCIt note : Neurexin-3-beta is proccessed by alpha-secretase, which leads to the formation of an extracellular soluble form and a C-terminal membrane-embedded fragment (CTF). Proteolysis of the CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides.;

NCI Metathesaurus CUI : CL508180;

Details

Origin ID

C126711;

UMLS CUI

C4287830;

OMIM relation
- Neurexin III [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- NRXN3 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Synaptic Junction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]

Keyword's position in hierarchy(ies) :

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